![]() “With this uncertainty about what would happen without Covid and without vaccination, it’s difficult for the regulatory authorities to make the comparisons they need to make. They say that in a million people followed up for a year (before Covid), somewhere between two and five might have a CVST, but then point out that more recent studies say it might be 13 or 16 cases, not two or five, and that this seems to be because data are being collected more carefully. “Just to point out how difficult this can be, a recent EMA report about blood clots looked at the background risk of CVST, one of the serious blood clotting disorders under consideration. The general population’s risk of cerebral venous sinus thrombosis (CVST) – one of the blood clot types observed in Vaxzevria recipients – is around five in a million slightly higher than the risk associated with the vaccine.Įmeritus professor of Applied Statistics at The Open University, Prof Kevin McConway, commented: “One thing that needs to be done in checking whether a possible vaccine adverse effect is actually caused by the vaccine is to compare how often the effect happened after vaccination, compared to how often it happens in healthy, unvaccinated people. What’s more, around 10,000 people usually develop blood clots in the EU in any given month, while an estimated 3,000 blood clot cases occur monthly in the UK. The MHRA said 11 of these people were under the age of 50, and three were younger than 30. Of the 79 UK blood clotting cases following a first dose of the AZ vaccine reported up to the end of March, 19 people have died. The agency said no causal relationship has been established at this stage. The EMA is also reviewing a potential link between Vaxzevria and five reported cases of capillary leak syndrome, a rare disorder characterised by the leakage of fluid from blood vessels, causing tissue swelling and a drop in blood pressure. Both regulators have said the benefits of the vaccine continue to outweigh the potential risks, and people should still get vaccinated when asked to. The EMA’s safety committee noted that the reported clots occurred in the brain, abdomen and arteries, and were associated with thrombocytopenia, or low levels of blood platelets. ![]() Now, less than a month later, both the EMA and the UK Medicines and Healthcare products Regulatory Agency (MHRA) have published reports confirming evidence of a possible link between AZ’s jab, now known as Vaxzevria, and “extremely rare” blood clot cases. What are the potential growth opportunities?.How might the Chinese government react?.Spotlight on Shanghai: what is the situation there?.What is the effect of lockdowns on Chinese ports?.What is the effect of lockdowns on foodservice?.Which multinational companies have been affected?.Access GlobalData’s new whitepaper, China in 2022: the impact of China’s Zero-COVID lockdowns on economic activity, consumer goods and the foodservice industry, to examine the current situation in Shanghai and other cities in China, to better understand the worst-affected industry sectors, foodservice in particular, and to explore potential growth opportunities as China recovers. COVID outbreaks in Shanghai, Beijing and many other Chinese cities will impact 2022’s economic growth as consumers and businesses experience rolling lockdowns, leading to a slowdown in domestic and international supply chains.Ĭhina’s Zero-COVID policy is having a demonstrable impact on consumer-facing industries. While wanting to protect the country from being overwhelmed by Omicron, China’s adherence to a Zero-COVID policy is resulting in a significant economic downturn.
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